The classification criteria were derived from a set of 702 expertrated patient scenarios. Evaluating the new 2018 acreular sle classification in. Derivation and validation of the systemic lupus international. Complex disease classifications and scores should be always available, easy to use and constantly updated according to the latest guidelines. Other criteria were chosen from 7 clinical constitutional, hematologic, neuropsychiatric, mucocutaneous, serosal, musculoskeletal, renal and 3 immunologic antiphospholipid antibodies, complement proteins, slespecific antibodies. Accuracy of medical record scoring of the sliccacr damage. Yet, the traditional cardiovascular risk equations such as framingham consistently underestimate the risk. This systemic lupus diagnostic criteria slicc calculator helps the classification and diagnosis of sle based on clinical and immunological criteria. How to monitor sle in routine clinical practice annals. For example, for the first time, the new criteria includes fever as a classification criterion, which receives 2 points if an infectious or other nonsle cause can be discounted. When in the mid19th century cazenave first used the name lupus erythematosus, sle was a rare and lifethreatening illness. Bicla requires patients to meet response criteria across the bilag2004 index, sledai2000 and pga.
Accaha cv risk calculator 20 estimate 10year risk for atherosclerotic cardiovascular disease revised cardiac risk index lee criteria rapid preop assessment using the revised cardiac risk index asymptomatic ica internal carotid artery stenosis surgical risk stratification gupta perioperative cardiac risk determine perioperative risk for a wide variety of surgeries postoperative. This health tool is based on the 2012 classification created. Objective accelerated atherosclerosis remains the major cause of late death after 5 years in sle. The 2012 slicc classification criteria for sle classify a patient as having sle if a the patient satisfies four of the criteria, including at least one clinical criterion and one immunologic. The sliccacr score has been independently validated. Objectives to derive and validate a new disease activity measure for systemic lupus erythematosus sle, the sle disease activity score sledas, with improved sensitivity to change as compared with sle disease activity index sledai, while maintaining high specificity and easiness of use. The slicc criteria for sle classification requires. Criteria are cumulative and need not be present concurrently.
The bilagbased combined lupus assessment bicla is another composite index used in clinical trials. Background systemic lupus erythematosus sle is a disease with an autoimmune origin, which occurs nine times more often in women than in men, and is especially. Gladman was a key facilitator in the development and validation of the sliccacr damage index. A score reduction, ie, the disappearance of a scored parameter, requires either the complete resolution of a disease manifestation or laboratory test value. In comparison, the 2018 acreular sle classification criteria uses a point system 2018slescore for 22 clinical and immunologic domains range. As the precursor of the slicc group, members of the nato conference on prognosis studies in sle which took place in 1985 in toronto, recognized the need for three instruments to better describe the prognosis of sle including the domains of disease activity, accumulated damage. Development of a systemic lupus erythematosus cardiovascular. Lupus erythematosus describes the typical rash of sle and the term systemic emphasises the potential for multiorgan involvement. Acr diagnostic guidelines johns hopkins arthritis center. Face rash, which doctors call a malar rash, that is butterfly shaped and covers the bridge of the nose and spreads across the cheeks. Pdf 2015 acrslicc revised criteria for diagnosis of. Acr clinical classification criteria for rheumatoid arthritis. Fever has recently been identified as a marker of earlystage sle in at least some patients, and its addition to the classification criteria adds a new dimension to. Feb 03, 2015 systemic lupus erythematosus sle is a heterogeneous, inflammatory, multisystem autoimmune disease in which antinuclear antibodies occur often years before clinical symptoms.
Usually, this disease with protean manifestations has a remitting relapsing course. From bilag to bilagbased combined lupus assessment30 years. Pointofcare tools in the areas of cardiology, internal medicine, nephrology, general practice, hematology, gastroenterology, emergency medicine, oncology, orthopedics, respirology, neurology. Methods we studied 520 patients with sle from two tertiary care centres derivation and. The traditional 1997 acr sle classification criteria classify a patient as having sle if 4 of the 11 criteria have been met over time. Iraj salehiabari 2015, 2015 acrslicc revised criteria for diagnosis of systemic lupus erythematosus. Other criteria were chosen from 7 clinical constitutional, hematologic, neuropsychiatric, mucocutaneous, serosal, musculoskeletal, renal and 3 immunologic antiphospholipid antibodies, complement proteins, slespecific antibodies categories, and weighted from 2 to 10. Mdcalc medical calculators, equations, scores, and. Rheumatologists need easy access to relevant and verified information to make informed decisions quickly. Slicc is a domain specific language for specifying cache coherence protocols. Jun 22, 2018 the new criteria allow for a shift in the way we think of the disease.
Steps should be followed sequentially, moving to the next step if the patients response proves inadequate. Gladman was a key facilitator in the development and validation of the slicc acr damage index. The subaxial cervical spine injury classification slic system is a classification system for subaxial cervical spine trauma that helps determine information about injury pattern and severity, in addition to treatment considerations and prognosis. Derivation and validation of the sle disease activity score. This differs from the sri in that the bilag2004 index is the driver of efficacy. New eularacr classification criteria for sle rheumnow. Jan 28, 2015 slicc12 also failed in classification, as it misclassified more cases from the control group than either acr82, acr97 or fries. Latest medical news and updates need to be easily accessible. Slicc criteria for sle slicc classification criteria for sle. Slicc criteria for sle slicc classification criteria for. Study evaluates slicc12 classification criteria for lupus.
Free online disease activity score dasdas28 calculators. In the text below the form there is information on the slicc, along with instructions on how to interpret the criteria that is present. To improve homogeneity of patient populations identified for. Systemic lupus erythematosus sle is a chronic autoimmune disorder that can affect any organ system of the body. Subaxial cervical spine injury classification slic system. Calculates stroke risk for patients with atrial fibrillation, possibly better than the chads. This article provides more detail on the differences between classification and diagnostic criteria, and why the. Recursive partitioning was used to derive an initial rule that was simplified and refined based on slicc physician consensus. Diagnosis and treatment of childhoodonset systemic lupus. Lights criteria pleural doctor answers on healthcaremagic. The new 2019 eularacr classification criteria for sle requires a positive ana as obligatory entry criterion.
We sought to construct a datadriven formula for cardiovascular risk in sle, based on data collected during the first year in a longitudinal cohort, for research purposes. Derivation and validation of the sle disease activity. New sle classification criteria reset disease definition. Calculates a corrected calcium level for patients with hypoalbuminemia. An online calculator can be used to calculate the slicc score.
Iraj salehiabari 2015, 2015 acr slicc revised criteria for diagnosis of systemic lupus erythematosus. This tool can average connection speed for any internet provider, country or city in the world. Calculates crcl according to the cockcroftgault equation. Their work included both a derivation and a validation of the new set of criteria as well as of acr97. Discoid lupus erythematosus, which characteristically manifests as cutaneous inflammation, scaling, and scarring, may lead to irreversible skin damage in the affected area. The acr has previously endorsed diagnostic criteria. Application of the 2012 systemic lupus international. Validation of the cutaneous lupus disease area and. Should anyone report such neutrophils in an asymptomatic person. Slicc12 also failed in classification, as it misclassified more cases from the control group than either acr82, acr97 or fries. How to monitor sle in routine clinical practice annals of. The criteria do not need to occur simultaneously and may have occurred over a number of monthsyears see cases, box 4. The slicc criteria the classification criteria that thus emerged were published in 2012, and is popularly called the slicc criteria table 2. Do you want to research connection speed for slicc.
The slicc group validated the classification criteria in a new validation sample of 690 new expertrated patient scenarios. Methods we studied 520 patients with sle from two tertiary care centres derivation and validation. The systemic lupus international collaborating clinics slicc network, devoted to clinical research in sle, presented a new set of classification criteria in 2012 slicc 12 based on the evaluation of almost 1,400 patient scenarios. Read by qxmd integration provides direct access to original research for a given tool. Assessment of fracture risk in a cohort of egyptian female. There are racial and ethnic variations, with higher rates reported in black and hispanic peoples 2. To accomplish increased sensitivity and specificity figures, a combination of criteria sets for clinical sle studies should be. The app is translated into 6 languages and active in more than 120 countries. Just to get an idea of what the scores mean, 0 to 5 is mild disease activity, 6 to 12 is moderate disease activity, and over 12 represents severe activity this is just a generalization. Looking for online definition of slic or what slic stands for. Slic is listed in the worlds largest and most authoritative dictionary database of abbreviations and acronyms the free dictionary. Dec 15, 2017 rheumatology researchers referred to both the 1997 acr revised criteria and 2012 systemic lupus international collaborating clinics slicc criteria when developing the new criteria, said martin aringer, md, steering committee cochair and chief of rheumatology at university medical center carl gustav carus in dresden, germany.
American college of rheumatology subcommittee on osteoarthritis guidelines. The acr supports criteria development projects in different topic areas related to rheumatic disease. If you have 4 out of 11 it is likely you have lupus. It contains 11 clinical and 6 immunological criteria. Its like when you mean to call someone thick but you say thicc instead. The slicc criteria are the culmination of an 8 year effort by a group of experts and this clinical expertise is reflected in it. The slicc classification criteria were derived from a set of 702 expertrated patient scenarios. It has an annual incidence of 5 per 100,000 of the general population 1. In this exploratory cross sectional study, 70 female sle patients aged 40 years or older satisfying at least four of slicc classification criteria were enrolled. The systemic lupus international collaborating clinics slicc network, devoted to clinical research in sle, presented a new set of classification criteria in 2012 slicc12 based on the evaluation of almost 1,400 patient scenarios. Remember, these are classification criteria and not diagnostic criteria and failure to meet the criteria does not exclude csle. Stratifies severity of endstage liver disease, for transplant planning. Pdf version slicc classification criteria for sle amith balachandran, department of anaesthesia, cmc vellore, and ashish jacob mathew, assistant professor, department of rheumatology, cmc, vellore. All ra patients met acreular 2010 criteria acpapositive but ananegative 31.
Here, we investigate the diagnostic associations of elevated sir and the potential use of igranl as a novel biomarker in sle. Gratis online disease activity score dasdas28 rekenmachine. Sliccacr damage index in afrocarribean patients with systemic lupus erythematosus. Projects generally focus on classification, response, and remission criteria. Systemic lupus erythematosis sle is diagnosed using 11 criteria. Accuracy of medical record scoring of the sliccacr damage index for systemic lupus erythematosus article in lupus 95. The compiler also generates an html specification of the protocol. To accomplish increased sensitivity and specificity figures, a combination of criteria sets for clinical sle studies should be considered, the authors recommended in the abstract. Rheumatology researchers referred to both the 1997 acr revised criteria and 2012 systemic lupus international collaborating clinics slicc criteria when developing the new criteria, said martin aringer, md, steering committee cochair and chief of rheumatology at university medical center carl gustav carus in dresden, germany. Slicc classification criteria for sle current medical. A list of items considered to reflect damage in sle was generated through a nominal group from the systemic lupus international collaborating clin ics slicc and the american college of rheumatology diagnostic and therapeutic criteria committee. Systemic lupus diagnostic criteria slicc calculator.